Skip to content
Davide Scuteri Moretti
Senior Data Architect
Home/Architectures/Scientific Research
Scientific Research
Client
PR Calabria FESR FSE 2021–2027 — partners: IRCCS San Raffaele, Università Magna Graecia, Romolo Hospital, More Care
Role
Lead Data Architect

SUN IN SEAD

Bio-Clinical Data Platform

Integrates clinical data, biobank provenance, NGS ground truth, Raman spectra and ML validation into a pseudonymised, traceable research platform.

Architecture Flow
PatientClinical identityClinical RequestPseudonymisedSample & BiobankProvenanceNGS & RamanAcquisitionGround truth · spectraPredictionML model outputsValidationNGS concordance
§ 01 Context

The platform separates direct patient identity from laboratory sample identity through pseudonymised identifiers, and integrates biobanks and external systems through REST, Kafka, JSON, XML, CSV and controlled file exchange, with authentication, API contracts, response codes and OpenAPI documentation.

§ 02 Designed System
Patient → Clinical Request → Sample → Biobank → NGS and Raman Acquisition → Prediction → Validation
Pseudonymised identifiers separating patient and laboratory-sample identity
Integration through REST, Kafka, JSON, XML, CSV and controlled file exchange
GDPR compliance, auditability and traceability between clinical requirements, software development and validation
§ 03 Capabilities
  • Provenance from patient to prediction
  • AI validation against NGS molecular ground truth
  • Traceable Raman spectrum preprocessing, feature extraction and model outputs
§ 04 Objects & Stack
Data Objects
  • Test definition
  • Biological samples
  • Biobank and reagent information
  • NGS molecular ground truth
  • Raman acquisition parameters
  • Raw and extracted spectral data
  • Predictions, confidence scores and concordance
  • Corrective actions and validation results
Technologies
PythonPostgreSQLKafkaRESTOpenAPISpark
§ 05 Outcome
Privacy

Pseudonymisation, GDPR compliance, auditability across clinical, engineering and validation domains.

§ 06 Related Reading